Allopurinol’s effect on caspase-3 and caspase-8 activity in hypoxic-ischemic newborn rats
نویسندگان
چکیده
منابع مشابه
Effects of Aerobic Training on Caspase-3 Expression and Apoptosis in Hippocampus of Rats after Brain Ischemic Stroke
Introduction: Although exercise is an effective strategy for preventing and treating stroke, the extent of this effect seems to depend on when exercise begins. Apoptosis plays a critical role after stroke. However, it is unclear whether early exercise inhibits apoptosis after stroke? The aim of this study was to determine the effect of eight weeks of early aerobic training after stroke inductio...
متن کاملThe Cytotoxic Effects of Testosterone on Gastric Cancer Cell Line (AGS) and Evaluation of Caspase-3, -8, and -9 Activity
Background and Objectives: Various studies have shown that sex steroids affect cancer cells at cellular and molecular level. In this study, the anti-proliferation effects of testosterone, was investigated on gastric cancer cell line (AGS) and activity level of caspase-3, -8 and -9, was evaluated. Methods: In this laboratory experimental study, AGS cell line, were randomly divided into contro...
متن کاملThe effects of indirect exposure of nanosilver on caspase-8 and caspase-9 levels in liver and brain of suckling rats
Objective(s): The adverse health effects of nanosilver (AgNp) on adult animal models have been well documented. However, data is scarce regarding the toxic effects of AgNp on sensitive developmental stages. The present study aimed to investigate the effects of maternal milk exposure to AgNp on apoptosis induction in the liver and brain of the offspring of rats. Materials and Methods: Lact...
متن کاملThe effect of progesterone on caspase 8, 9 and 3 activity and investigation of morphological changes in MCF-7 cells nuclei
Background and Objective: : Studies have shown that progesterone is effective in inducing apoptosis in cancer cells. This study aimed to evaluate the effect of progesterone on the activity of caspases 8, 9, and 3 and to investigate morphological changes in MCF-7 cell nuclei. Materials and Methods: In this experimental study, MCF-7 cells were purchased from the Bank of Pasteur Institute of Iran...
متن کاملMetalloporphyrins inactivate caspase-3 and -8.
Activation of caspases represents one of the earliest biochemical indicators for apoptotic cell death. Therefore, measurement of caspase activity is a widely used and generally accepted method to determine apoptosis in a wide range of in vivo and in vitro settings. Numerous publications characterize the role of the heme-catabolizing enzyme heme oxygenase-1 (HO-1) in regulating apoptotic process...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Türk Pediatri Arşivi
سال: 2013
ISSN: 1306-0015,1308-6278
DOI: 10.4274/tpa.986